In a series of controlled battery trials,
Rofenaid (at doses ranging from 0.02 to 0.12% active
drug in feed) was administered to ducklings infected experimentally with Pasteurella anatipestifer and Escherichia coli strains. Against P. anatipestifer,
Rofenaid at 0.02 to 0.12% levels in feed either prevented or reduced mortality, gross lesions, and bacterial isolations. Furthermore, the
weight gain and feed conversion of infected
Rofenaid-medicated ducklings were superior to those of uninfected unmedicated controls in two out of three trials. Against E. coli,
Rofenaid at 0.02 to 0.08% levels in feed either prevented or reduced mortality, gross lesions, and bacterial isolations.
Weight gain and feed conversion of infected
Rofenaid-medicated ducklings were also superior to those of uninfected unmedicated controls in two out of three trials. It appears that
Rofenaid, at a 0.02-0.08% level, controls
infections in ducklings caused by P. anatipestifer and E. coli strains sensitive to this compound.