Mitogenic response to Toxocara antigen and chemotactic defect in visceral larva migrans.

Abstract	A 3-year-old girl had the typical features of visceral larva migrans syndrome, including hypereosinophilia, recurrent pulmonary infiltrates, and elevated serum IgG, IgE, and isohemagglutinin titers. A marked mitogenic response of her cultured lymphocytes to Toxocara antigen but not to Ascaris antigen was found. A neutrophil chemotactic abnormality ot Escherichia coli culture filtrates and zymosan-activated sera was also demonstrated, which partially corrected after she was treated with diethylcarbamazine citrate.
Authors	K Caldwell, M Lobell, P F Coccia
Journal	American journal of diseases of children (1960) (Am J Dis Child) Vol. 134 Issue 9 Pg. 845-7 (Sep 1980) ISSN: 0002-922X [Print] United States
PMID	6998281 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References	Antigens
Topics	Antigens Chemotaxis, Leukocyte Child, Preschool Escherichia coli (immunology) Female Humans Larva Migrans, Visceral (diagnosis, immunology) Lymphocyte Activation Neutrophils Toxocara (immunology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!