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Apparent Glucantime failure in five patients with mucocutaneous leishmaniasis.

Abstract
The case histories of five patients initially resistant to Glucantime therapy are presented. In addition comments are made on each patient since they demonstrated unusual clinical features. The practical difficulties in assessing true resistance to Glucantime are briefly discussed.
AuthorsR A Rocha, R N Sampaio, M Guerra, A Magalhâes, C C Cuba, A C Barreto, P D Marsden
JournalThe Journal of tropical medicine and hygiene (J Trop Med Hyg) Vol. 83 Issue 4 Pg. 131-9 (Aug 1980) ISSN: 0022-5304 [Print] England
PMID6997505 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • Antigens
  • Organometallic Compounds
  • Sorbitol
  • Meglumine
  • Meglumine Antimoniate
  • Amphotericin B
  • Antimony
Topics
  • Amphotericin B (adverse effects, therapeutic use)
  • Antigens (immunology)
  • Antimony (therapeutic use)
  • Brazil
  • Female
  • Fluorescent Antibody Technique
  • Humans
  • Leishmania (immunology)
  • Leishmaniasis, Mucocutaneous (drug therapy, immunology)
  • Meglumine (therapeutic use)
  • Meglumine Antimoniate
  • Middle Aged
  • Organometallic Compounds
  • Sorbitol (analogs & derivatives)

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