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[Recent findings in the field of humoral immunology in syphilis].

Abstract
Investigations on 404742 sera by the Automated Micro-Haemagglutination Assay with Treponema pallidum Antigen (AMHA-TP) and the VDRL-test for screening revealed 9848 (2,43%) reactive results in one of the two or in both methods. All reactive samples were checked by the FTA-ABS-test. A reactivity in both, the AMHA-TP and the FTA-ABS indicates a former infection with Treponema pallidum. The VDRL failed to point out reactivity in 4226 of 7474 sera (56,5%) deriving from syphilitic donors. The agglutination in the AMHA-TP can be inhibited by a protein of low molecular weight which occurs appearently in extraordinarily rare cases and was found in one sample only until now. The margin of error of the screening procedure by using the AMHA-TP and the VDRL amounts to 0,04%-0,38% of all samples examined.
AuthorsA Luger
JournalDermatosen in Beruf und Umwelt. Occupation and environment (Derm Beruf Umwelt) Vol. 28 Issue 2 Pg. 48-50 ( 1980) ISSN: 0343-2432 [Print] Germany
Vernacular TitleNeuere Erkenntnisse auf dem Gebiet der humoralen Immunologie bei Syphilis.
PMID6996979 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Immunoglobulin G
Topics
  • Agglutination Tests
  • Antibody Formation
  • Humans
  • Immunoglobulin G (immunology)
  • Syphilis (immunology)
  • Syphilis Serodiagnosis
  • Treponema pallidum (immunology)

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