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Identification of 15 beta-hydroxylated C21 steroids in the neo-natal period: the role of 3 alpha,15 beta,17 alpha-trihydroxy-5 beta-pregnan-20-one in the perinatal diagnosis of congenital adrenal hyperplasia (CAH) due to a 21-hydroxylase deficiency.

AuthorsG E Joannou
JournalJournal of steroid biochemistry (J Steroid Biochem) Vol. 14 Issue 9 Pg. 901-12 (Sep 1981) ISSN: 0022-4731 [Print] England
PMID6975400 (Publication Type: Journal Article)
Chemical References
  • 15 beta,17 alpha,20 beta-trihydroxy-4-pregnen-3-one
  • Pregnenes
  • Pregnanetriol
  • 17-alpha-Hydroxypregnenolone
  • 3 beta,15 beta,17 alpha-trihydroxy-5-pregnen-20-one
  • 3,15,17-trihydroxypregnan-20-one
  • Steroid Hydroxylases
Topics
  • 17-alpha-Hydroxypregnenolone (analogs & derivatives, urine)
  • Adrenal Hyperplasia, Congenital (diagnosis, etiology)
  • Amniotic Fluid (metabolism)
  • Female
  • Gas Chromatography-Mass Spectrometry
  • Humans
  • Infant
  • Infant, Newborn
  • Infant, Newborn, Diseases (diagnosis)
  • Penicillium (analysis)
  • Pregnancy
  • Pregnanetriol (urine)
  • Pregnenes (isolation & purification)
  • Steroid Hydroxylases (deficiency)

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