[Therapeutic results in malignant lymphomas treated by the COPP and POPP drug administration schedules].

Abstract

The paper deals with a comparison of the results of treatment of 19 patients with malignant lymphomas, mostly diffuse ones, stage 3, by POPP schedule (paphencyl, vincristine (oncovine), procarbosin (natulan) and prednisolone) and 37 similar patients who received a modified standard COPP treatment. Following six courses of POPP treatment, the frequency of complete remission was significantly higher (83 and 51% respectively). Therefore, this schedule of therapy may be recommended for a large-scale application. The assessment of the survival rates of patients who received either type of treatment required further study.

• Authors: L I Iavorkovskiĭ, A Ia Rotsena, O Iu Udris, R Ia Bliumental', M A Zile
• Journal: Voprosy onkologii (Vopr Onkol) Vol. 27 Issue 4 Pg. 34-9 ( 1981) ISSN: 0507-3758 [Print] Russia (Federation)
• Vernacular Title: Rezul'taty lecheniia po skhemam TsOPP i POPP bol'nykh zlokachestvennymi limfomami.
• PMID: 6972123 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Nitrogen Mustard Compounds
• para-Aminobenzoates
• Procarbazine
• pafencil
• Vincristine
• Cyclophosphamide
• Prednisolone
• 4-Aminobenzoic Acid

Topics

• 4-Aminobenzoic Acid (administration & dosage)
• Adult
• Aged
• Cyclophosphamide (administration & dosage)
• Drug Administration Schedule
• Drug Evaluation
• Drug Therapy, Combination
• Female
• Humans
• Lymphoma (drug therapy, mortality)
• Male
• Middle Aged
• Nitrogen Mustard Compounds (administration & dosage)
• Prednisolone (administration & dosage)
• Procarbazine (administration & dosage)
• Vincristine (administration & dosage)
• para-Aminobenzoates