[Non-Hodgkin's malignant lymphoma: reliability of "typing" using cyto-enzymatic markers. Comparison with immunological markers (author's transl)].

Abstract

Comparison between membrane markers and enzyme markers was made in 74 cases of non-Hodgkin's malignant lymphomas and a good correlation appears between both methods in order to distinct lymphomas into T and B origin. Enzyme markers are reliable and provide quickly made and easily interpretable documents. As far as T-lymphomas are concerned, three hydrolases namely acid phosphates e, acid esterase and B-glucuronidase give the same good results. As for B-lymphomas, a specific enzyme marker has to be found. Furthermore, typing of malignant lymphomas by enzymatic and/or immunologic methods appears to be quite better than from morphologic features such as convoluted or cleaved nuclei for example.

• Authors: C Micheau, A Bernard, E Pujade, D Belpomme, C Carlu, B Clausse
• Journal: La Nouvelle presse medicale (Nouv Presse Med) Vol. 9 Issue 3 Pg. 167-70 (Jan 12 1980) ISSN: 0301-1518 [Print] France
• Vernacular Title: Lymphomes malins non hodgkiniens: fiabilité du "typage" par les marqueurs cyto-enzymatiques. Comparaison avec les marqueurs immunologiques.
• PMID: 6965535 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Esterases
• Alkaline Phosphatase
• Acid Phosphatase
• Glucuronidase

Topics

• Acid Phosphatase (metabolism)
• Alkaline Phosphatase (metabolism)
• B-Lymphocytes (immunology)
• Esterases (metabolism)
• Glucuronidase (metabolism)
• Humans
• Lymphoma (diagnosis, enzymology, immunology)
• Methods
• T-Lymphocytes (immunology)