HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

HLA--Bw54 (Bw22-J, J-1) antigen in juvenile onset diabetes mellitus in Japan.

Abstract
HLA--B8 and/or Bw15, associated with juvenile onset insulin-dependent diabetes mellitus (JDM) in Caucasians, have a very low frequency in the Japanese population. Thus, we were interested in investigating the association between JDM and HLA antigen in a Japanese population. Eighty-nine patients with JDM and 128 unrelated random controls were HLA-typed by the microlymphocytotoxicity test. The data revealed a significant, positive association between this type of diabetes mellitus and HLA--Bw54 (Bw22-J, J-1) antigen (Japanese-specific split antigen of HLA--Bw22).
AuthorsK Okimoto, T Juji, S Ishiba, H Maruyama, H Tohyama, K Kosaka
JournalTissue antigens (Tissue Antigens) Vol. 11 Issue 5 Pg. 418-22 (May 1978) ISSN: 0001-2815 [Print] England
PMID694905 (Publication Type: Journal Article)
Chemical References
  • HLA Antigens
Topics
  • Cytotoxicity Tests, Immunologic
  • Diabetes Mellitus, Type 1 (genetics)
  • Female
  • HLA Antigens (analysis)
  • Humans
  • Japan
  • Male
  • Risk

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: