SEM observation of cultured, mitogen-stimulated leukocytes. Cells obtained from patients with acute myeloblastic and chronic lymphocytic leukemias.

Abstract

SEM observation of acute myeloblastic leukemia cells, incubated for 20 h with the mitogens pokeweed and phytohaemagglutinin, showed these to have elongated structures that were either smooth or partially covered by thumblike figures. By contrast, the chronic lymphocytic leukemia cells possessed more compact shapes and some were covered with blebs of varying sizes.

• Authors: E D Lalague, A A Abugaber, S Haviernick, M R Corvellec, L Pelletier, C Derghazarian, G H Cousineau
• Journal: Experientia (Experientia) Vol. 38 Issue 1 Pg. 90-2 (Jan 15 1982) ISSN: 0014-4754 [Print] Switzerland
• PMID: 6948687 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Phytohemagglutinins
• Pokeweed Mitogens

Topics

• Cell Membrane (ultrastructure)
• Cells, Cultured
• Humans
• Leukemia, Lymphoid (ultrastructure)
• Leukemia, Myeloid, Acute (ultrastructure)
• Lymphocytes (ultrastructure)
• Microscopy, Electron, Scanning
• Monocytes (ultrastructure)
• Phytohemagglutinins (pharmacology)
• Pokeweed Mitogens (pharmacology)