| Abstract | A case of acute inflammatory polyradioculoneuropathy (IPN, Guillain-Barré syndrome) not responding to oral corticosteroids but showing marked improvement on parenteral corticosteroids is reported. Oral prednisone 60 mg/day was begun on hospital admission and increased after one week to 100 mg/day; however, the patient's respiratory function, demonstrated by forced vital capacity, continued to deteriorate. Improvement was noted when the patient was switched to intravenous methyl-prednisolone 100 mg/day. Further attempts to use oral corticosteroids (including oral methyl-prednisolone 96 mg/day) resulted in deterioration of the patient's function. |
| Authors | R A Brumback |
| Journal | Australian and New Zealand journal of medicine
(Aust N Z J Med)
Vol. 10
Issue 2
Pg. 224-6
(Apr 1980)
ISSN: 0004-8291 AUSTRALIA |
| PMID | 6930216
(Publication Type: Case Reports, Journal Article)
|
| Chemical References |
- Prednisolone
- Methylprednisolone
|
| Topics |
- Administration, Oral
- Adolescent
- Biological Availability
- Humans
- Infusions, Parenteral
- Male
- Methylprednisolone
(administration & dosage, metabolism)
- Polyradiculoneuropathy
(drug therapy)
- Prednisolone
(administration & dosage, metabolism)
|
