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Subclinical hypothyroidism.

Abstract
Clinical and biochemical indices of thyroid function were compared in 18 euthyroid control subjects and 54 patients at risk of developing hypothyroidism, and the assessment repeated after a four-week trial of oral triiodothyronine (T3) 40 microgram daily. Patients with minor elevation of the pre-treatment serum TSH concentration (5-15 microU/ml) showed significant reduction in the free thyroxine index (FTI), prolongation of the basal ankle reflex half-relasation time (ART), and shortening of the ART after oral T3 treatment, when compared either to control subjects or to patients with a normal TSH level. It is concluded that patients with minimal TSH elevation have minor but parallel abnormalities of both thyroid hormone concentration and action.
AuthorsM S Croxson, H K Ibbertson
JournalThe New Zealand medical journal (N Z Med J) Vol. 91 Issue 653 Pg. 89-91 (Feb 13 1980) ISSN: 0028-8446 [Print] New Zealand
PMID6929968 (Publication Type: Journal Article)
Chemical References
  • Thyroid Hormones
  • Triiodothyronine
  • Thyrotropin
Topics
  • Humans
  • Hypothyroidism (blood, drug therapy)
  • Thyroid Function Tests
  • Thyroid Hormones (blood)
  • Thyrotropin (blood)
  • Triiodothyronine (therapeutic use)

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