| Abstract | Clinical and biochemical indices of thyroid function were compared in 18 euthyroid control subjects and 54 patients at risk of developing hypothyroidism, and the assessment repeated after a four-week trial of oral triiodothyronine (T3) 40 microgram daily. Patients with minor elevation of the pre-treatment serum TSH concentration (5-15 microU/ml) showed significant reduction in the free thyroxine index (FTI), prolongation of the basal ankle reflex half-relasation time (ART), and shortening of the ART after oral T3 treatment, when compared either to control subjects or to patients with a normal TSH level. It is concluded that patients with minimal TSH elevation have minor but parallel abnormalities of both thyroid hormone concentration and action. |
| Authors | M S Croxson, H K Ibbertson |
| Journal | The New Zealand medical journal
(N Z Med J)
Vol. 91
Issue 653
Pg. 89-91
(Feb 13 1980)
ISSN: 0028-8446 NEW ZEALAND |
| PMID | 6929968
(Publication Type: Journal Article)
|
| Chemical References |
- Thyroid Hormones
- Triiodothyronine
- Thyrotropin
|
| Topics |
- Humans
- Hypothyroidism
(blood, drug therapy)
- Thyroid Function Tests
- Thyroid Hormones
(blood)
- Thyrotropin
(blood)
- Triiodothyronine
(therapeutic use)
|
