[Comparative study of the antiglaucomatous activity of Glauplex 2 and pilocarpine nitrate on alpha-chymotrypsin-induced experimental glaucoma].

Abstract

The antiglaucomatous effects of Glauplex 2 and pilocarpine nitrate on alpha-chymotrypsine-induced experimental glaucoma were studied in 8 rabbits. Changes in intraocular pressure were measured over a period of 12 hours after a single instillation of Glauplex 2 or two instillations of 2.6 p. cent pilocarpine nitrate at t = 0 and t = 6 hours. The antihypertensive effect of a single instillation of Glauplex 2 was shown to be approximately equivalent to that of two instillations of 2.6 p. cent pilocarpine nitrate.

• Authors: G Andermann, G de Burlet, C Cannet
• Journal: Journal francais d'ophtalmologie (J Fr Ophtalmol) Vol. 5 Issue 8-9 Pg. 499-504 ( 1982) ISSN: 0181-5512 [Print] France
• Vernacular Title: Etude comparative de l'activité antiglaucomateuse de Glauplex 2 et du nitrate de pilocarpine sur le glaucome expérimental à l'alpha-chymotrypsine.
• PMID: 6897256 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Delayed-Action Preparations
• Ophthalmic Solutions
• Pilocarpine
• Piloplex
• Chymotrypsin

Topics

• Animals
• Chymotrypsin
• Delayed-Action Preparations
• Disease Models, Animal
• Glaucoma (chemically induced, drug therapy)
• Ophthalmic Solutions
• Pilocarpine (therapeutic use)
• Rabbits
• Tonometry, Ocular