[Cyclophosphamide haemorragic cystitis in a child. Radiological and endoscopic aspects (author's transl)].

Abstract

Haemorragic cystitis is a well known complication of cyclophosphamide therapy. In the reported case, a 7 years old boy treated for lymphosarcoma, as an excretory urogram demonstrated important focal irregularity of the bladder wall. Cystoscopy revealed areas of important bullous oedema with generalized hyperemia. A biopsy disclosed normal urothelium raised by oedematous and congestive chorion and excluded a malignant tumor. Various kinds of endoscopic and surgical procedures are reported to control persisting hematuria after withdrawal of the cyclophosphamide treatment.

• Authors: P Sauvage, J Bientz, A Boilletot, J P Bringer, J P Bellocq, P Buck
• Journal: Chirurgie pediatrique (Chir Pediatr) 1982 Mar-Apr Vol. 23 Issue 2 Pg. 125-7 ISSN: 0180-5738 [Print] France
• Vernacular Title: Cystite hémorragique au cyclophosphamide chez un enfant. Aspects radiologiques et endoscopiques.
• PMID: 6896169 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Cyclophosphamide

Topics

• Child
• Cyclophosphamide (adverse effects, therapeutic use)
• Cystitis (chemically induced, diagnosis)
• Cystoscopy
• Hematuria (chemically induced)
• Hemorrhage (chemically induced)
• Humans
• Lymphoma, Non-Hodgkin (drug therapy)
• Male
• Pharyngeal Neoplasms (drug therapy)
• Urinary Bladder (pathology)
• Urography