[Morphine intrathecally - in postoperative and cancer-induced pain (author's transl)].

Abstract

Morphine 2 mg was injected directly into the intrathecal space in 33 patients. In the nonoperative group (group I) morphine was given with 2 ml saline solution; in the operative group (group II, 21 patients) morphine was given with 2 ml 10% glucose solution immediately before induction of anaesthesia. The onset of pain relief occurred after 12 to 35 min and the duration of analgesia was 14 and 18 35 min and the duration of analgesia was 14 and 48 hours. In group II we observed in respiratory depression 3 cases and in one case bladder insufficiency after morphine. In group I bladder insufficiency occurred in 2 cases. The disturbed bladder function recovered spontaneously in a few hours after morphine application. Respiratory depression was treated successfully with naloxone.

• Authors: E Gebert, J Sarubin, K A Yoeung
• Journal: Der Anaesthesist (Anaesthesist) Vol. 29 Issue 12 Pg. 653-5 (Dec 1980) ISSN: 0003-2417 [Print] Germany
• Vernacular Title: Morphin intrathekal - zur Bekaämpfung von tumorbedingten und postoperativen Schmerzen.
• PMID: 6894218 (Publication Type: English Abstract, Journal Article)

Chemical References

• Morphine

Topics

• Adult
• Aged
• Female
• Humans
• Injections, Spinal
• Male
• Middle Aged
• Morphine (administration & dosage, therapeutic use)
• Neoplasms (complications)
• Pain (drug therapy, etiology)
• Pain, Postoperative (drug therapy)