Abstract |
The effects of 3 or 6 days of starvation on hepatic peroxisomal palmitoyl-CoA oxidation were examined in adult lean and obese Zucker rats. When expressed either per mg of DNA or per total liver, obese rats had almost 2-fold higher oxidation rates than the lean rats. Within 6 days of starvation rates fell by 50% among both phenotypes. When data were expressed per 100 g body wt., lean and obese rats had similar rates, falling from a mean of 0.57 to 0.28 mumol/min per 100 g body wt. within 6 days of starvation. Peroxisomal oxidative changes paralleled mitochondrial beta-oxidative changes.
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Authors | P S Brady, C L Hoppel |
Journal | The Biochemical journal
(Biochem J)
Vol. 212
Issue 3
Pg. 891-4
(Jun 15 1983)
ISSN: 0264-6021 [Print] England |
PMID | 6882399
(Publication Type: Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.)
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Chemical References |
- Acyl Coenzyme A
- NAD
- Palmitoyl Coenzyme A
- Catalase
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Topics |
- Acyl Coenzyme A
(metabolism)
- Animals
- Catalase
(metabolism)
- Female
- Liver
(metabolism)
- Male
- Microbodies
(metabolism)
- NAD
(metabolism)
- Obesity
(metabolism)
- Organ Size
- Organoids
(metabolism)
- Oxidation-Reduction
- Palmitoyl Coenzyme A
(metabolism)
- Rats
- Rats, Zucker
- Starvation
(metabolism)
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