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[Effect of intravenous disopyramide in supraventricular paroxysmal tachycardia refractory to vagal maneuvers].

Abstract
The objective of this study was to prove the efficacy of intravenous disopyramide in the treatment of paroxysmal supraventricular tachycardia resistant to vagal maneuvers. Nine patients with this condition were admitted to the emergency service of the Instituto Nacional de Cardiología Ignacio Chávez. They were given an intravenous bolus of 2 mg/kg of the drug a maintenance dose of 0.4 mg/kg during 3 hours. The undesirable effects of the drug were arterial hypotension, dizziness, dry mouth, transient A-V dissociation and scape-capture rhythm. In conclussion, disopyramide is an excellent drug in the treatment of paroxysmal supra-ventricular tachycardia resistant to vagal maneuvers, but an strict monitorization of the arterial pressure and electrocardiogram should be kept during its administration.
AuthorsL C Romero-Ayala, J Soní
JournalArchivos del Instituto de Cardiologia de Mexico (Arch Inst Cardiol Mex) 1983 Mar-Apr Vol. 53 Issue 2 Pg. 147-51 ISSN: 0020-3785 [Print] Mexico
Vernacular TitleEfecto de la disopiramida intravenosa en la taquicardia paroxistica supraventricular refractaria a maniobras vagales.
PMID6882095 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Pyridines
  • Disopyramide
Topics
  • Adult
  • Aged
  • Arrhythmias, Cardiac (chemically induced)
  • Disopyramide (administration & dosage, adverse effects, therapeutic use)
  • Female
  • Humans
  • Hypotension (chemically induced)
  • Injections, Intravenous
  • Male
  • Middle Aged
  • Pyridines (therapeutic use)
  • Tachycardia, Paroxysmal (drug therapy)

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