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Effects of lasalocid or monensin on legume or grain (feedlot) bloat.

Abstract
Doses of .66 to .99 mg monensin/kg body weight reduced legume bloat in cattle about 66% when compared with pretreatment bloat scores. Similar doses of lasalocid reduced legume bloat about 26%. A dose of 44 mg poloxalene/kg body weight (recommended dose for field use) reduced legume bloat 100%. Monensin or lasalocid combined with 25 or 50% of the recommended dose of poloxalene reduced bloat under that of the antibiotics alone, but did not achieve 100% reduction. The antibiotic thiopeptin provided no preventive effect on legume bloat. Lasalocid, monensin or an experimental polyether antibiotic (X-14,547 A) at a dose of 1.32 mg/kg body weight when tested on cattle bloated on high grain diets reduced bloat by 92, 64 and 25%, respectively. Lasalocid at .66 mg/kg effectively prevented bloat from developing when given to animals before the feeding of high grain diets; however, a 1.32-mg dose was required to control bloat in cattle that were already bloating before they were given lasalocid. A dose of 1.32 mg salinomycin was ineffective in controlling grain bloat.
AuthorsE E Bartley, T G Nagaraja, E S Pressman, A D Dayton, M P Katz, L R Fina
JournalJournal of animal science (J Anim Sci) Vol. 56 Issue 6 Pg. 1400-6 (Jun 1983) ISSN: 0021-8812 [Print] United States
PMID6874619 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Anti-Bacterial Agents
  • Antimicrobial Cationic Peptides
  • Furans
  • Indenes
  • Peptides
  • thiopeptin
  • X 14547-A
  • Poloxalene
  • Monensin
  • Lasalocid
Topics
  • Animals
  • Anti-Bacterial Agents (therapeutic use)
  • Antimicrobial Cationic Peptides
  • Cattle
  • Cattle Diseases (prevention & control)
  • Disease Susceptibility
  • Drug Therapy, Combination
  • Edible Grain (adverse effects)
  • Fabaceae (adverse effects)
  • Female
  • Furans (therapeutic use)
  • Indenes (therapeutic use)
  • Lasalocid (therapeutic use)
  • Monensin (therapeutic use)
  • Peptides (therapeutic use)
  • Plants, Medicinal
  • Poloxalene (therapeutic use)
  • Rumen
  • Stomach Diseases (prevention & control, veterinary)

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