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Renal immunoblastic sarcoma complicating immunosuppressive therapy for Wegener granulomatosis.

Abstract
A renal tumor developing in a patient receiving cyclophosphamide (Cytoxan) therapy for Wegener granulomatosis is reported. The tumor was similar histologically to the "immunoblastic" sarcoma that develops in renal allograft recipients as a complication of immunosuppressive therapy. This case report strengthens the cause and effect relationship between immunosuppressive drug usage and the subsequent development of neoplasia.
AuthorsG R Sant, A A Ucci Jr, E M Meares Jr
JournalUrology (Urology) Vol. 21 Issue 6 Pg. 632-4 (Jun 1983) ISSN: 0090-4295 [Print] United States
PMID6868239 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Cyclophosphamide
  • Prednisone
Topics
  • Aged
  • Cyclophosphamide (administration & dosage, adverse effects)
  • Female
  • Granulomatosis with Polyangiitis (drug therapy)
  • Humans
  • Kidney Neoplasms (chemically induced)
  • Lymphoma (chemically induced)
  • Prednisone (administration & dosage)

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