Dermatitis from purified sea algae toxin (debromoaplysiatoxin).

Abstract	Cutaneous inflammation was induced by debromoaplysiatoxin, a purified toxin extracted from Lyngbya majuscula Gomont. This alga causes a seaweed dermatitis that occurs in persons who have swum off the coast of Oahu in Hawaii. By topical application, the toxin was found to produce an irritant pustular folliculitis in humans and to cause a severe cutaneous inflammatory reaction in the rabbit and in hairless mice.
Authors	A E Solomon, R B Stoughton
Journal	Archives of dermatology (Arch Dermatol) Vol. 114 Issue 9 Pg. 1333-5 (Sep 1978) ISSN: 0003-987X [Print] United States
PMID	686747 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
Chemical References	Lactones Lyngbya Toxins Marine Toxins debromoaplysiatoxin
Topics	Animals Dermatitis, Contact (etiology, pathology) Female Humans Lactones (toxicity) Lyngbya Toxins Male Marine Toxins Mice Mice, Inbred Strains Rabbits Seaweed Skin (pathology)

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