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Effect of orally administered polysaccharide from kefir grain on delayed-type hypersensitivity and tumor growth in mice.

Abstract
The effect of oral administration of a polysaccharide (KGF-C), isolated from the kefir grain, on delayed-type hypersensitivity (DTH) induced by picryl chloride and on the growth of solid tumor was examined in mice. KGF-C caused an increase in DTH response in intact mice and also tumor-bearing mice. The growth of tumor inoculated after the DTH test was markedly inhibited in the groups with high DTH response. A significant correlation between the DTH response and the antitumor activity was observed in intact mice.
AuthorsM Murofushi, M Shiomi, K Aibara
JournalJapanese journal of medical science & biology (Jpn J Med Sci Biol) Vol. 36 Issue 1 Pg. 49-53 (Feb 1983) ISSN: 0021-5112 [Print] Japan
PMID6865102 (Publication Type: Journal Article)
Chemical References
  • Polysaccharides
Topics
  • Administration, Oral
  • Animals
  • Dairy Products
  • Hypersensitivity, Delayed
  • Male
  • Mice
  • Mice, Inbred Strains
  • Neoplasms, Experimental (drug therapy, immunology)
  • Polysaccharides (pharmacology)

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