Correlation of leukocyte accumulation with chemotactic activity in the exudate of an allergic air-pouch inflammation.

Abstract

Chemotactic activity at the site of an allergic air-pouch inflammation induced with azobenzene-arsonate-conjugated acetyl bovine serum albumin as an antigen was studied and a close correlation of the chemotactic activity with the intensity of leukocyte migration was demonstrated. In the period of vigorous leukocyte immigration into the fluid in the allergic air-pouch, chemotactic activity of the exudate was maintained at a high level, while no significant activity was detected after the number of leukocytes in the pouch fluid reached maximum.

• Authors: A Kurihara, K Ohuchi, S Tsurufuji
• Journal: International archives of allergy and applied immunology (Int Arch Allergy Appl Immunol) Vol. 71 Issue 4 Pg. 368-70 ( 1983) ISSN: 0020-5915 [Print] Switzerland
• PMID: 6862665 (Publication Type: Journal Article)

Chemical References

• p-Azobenzenearsonate

Topics

• Animals
• Chemotaxis, Leukocyte
• Exudates and Transudates (cytology, immunology)
• Inflammation (immunology)
• Male
• Rats
• Rats, Inbred Strains
• Skin Tests
• Time Factors
• p-Azobenzenearsonate (immunology)