[Short-term effects of proglumetacin in arthrosis].

Abstract

Proglumetacin was administered as a sole treatment during 15 days at 450 mg/day to 20 patients with osteoarthritis localized in several joints. Within the observation period, pain at rest and on loading, joint mobility and morning stiffness improved significantly. Tolerance also resulted very good, as only two patients reported mild and transient gastric upsets. The peculiar combination of good efficacy also in short-term treatment and very good tolerance, points to proglumetacin as a drug of choice for the ambulatory management also of degenerative-reactive joint disorders.

• Authors: R Marcolongo, N Giordano, A Fioravanti
• Journal: Minerva medica (Minerva Med) Vol. 74 Issue 26 Pg. 1521-4 (Jun 23 1983) ISSN: 0026-4806 [Print] Italy
• Vernacular Title: Efficacia a breve termine della proglumetacina nell'artrosi.
• PMID: 6856163 (Publication Type: English Abstract, Journal Article)

Chemical References

• Indoleacetic Acids
• proglumetacin

Topics

• Drug Evaluation
• Drug Tolerance
• Humans
• Indoleacetic Acids (therapeutic use)
• Joint Diseases (drug therapy)
• Muscle Rigidity (drug therapy)
• Pain (drug therapy)