[Clinical study on long acting amoxicillin in urinary tract infection].

Abstract

Amoxicillin (AMPC), a widely used oral penicillin exhibites a strong bactericidal activity and a high level of safety. In the present study we administered L-AMPC, long acting AMPC granule, to 18 cases with urinary tract infections and obtained the following clinical results. 1. In all cases with acute simple cystitis, the effect was excellent. 2. Of 12 cases with chronic complicated UTI, the effect was excellent in 1 case, good in 4 cases and no effect was noted in 7 cases. The efficacy rate was 41.7%. 3. No side effects nor abnormal values in the laboratory examinations were noted. 4. Sixteen of 18 cases reported that this preparation was very agreeable to take compared with other powder type drugs, capsules and tablets. From these results we can confidently state that L-AMPC is a highly useful drug combining the excellent properties of AMPC, the convenience of b.i.d. dosage which improves patients compliance and satisfactory efficacy.

• Authors: K Mitobe, A Nishio, A Takamizawa, Y Kumamoto
• Journal: The Japanese journal of antibiotics (Jpn J Antibiot) Vol. 36 Issue 2 Pg. 408-14 (Feb 1983) ISSN: 0368-2781 [Print] Japan
• PMID: 6854940 (Publication Type: English Abstract, Journal Article)

Chemical References

• Delayed-Action Preparations
• Amoxicillin

Topics

• Adult
• Aged
• Amoxicillin (therapeutic use)
• Delayed-Action Preparations
• Female
• Humans
• Male
• Middle Aged
• Urinary Tract Infections (drug therapy)