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Prostatic acid phosphatase: comparison of radioimmunoassay and enzyme activity assay.

Abstract
Aspects of the clinical use of an enzymatic assay and a double antibody radioimmunoassay for prostatic acid phosphatase are compared. Standard blood sample collection and transport did not have a negative effect on the results of either assay. Our results show no substantial advantage in the use of a radioimmunoassay but emphasize the reliability of the enzymatic assay using alpha-naphthylphosphate as a substrate with respect to its predictive value and specificity in diagnosis and followup of patients with prostatic carcinoma.
AuthorsH J Mensink, J Marrink, F R Hindriks, A K van Zanten
JournalThe Journal of urology (J Urol) Vol. 129 Issue 6 Pg. 1136-40 (Jun 1983) ISSN: 0022-5347 [Print] United States
PMID6854787 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Naphthalenes
  • Organophosphorus Compounds
  • naphthyl phosphate
  • Acid Phosphatase
Topics
  • Acid Phosphatase (blood)
  • Adolescent
  • Adult
  • Aged
  • Clinical Enzyme Tests
  • Female
  • Humans
  • Male
  • Middle Aged
  • Naphthalenes
  • Organophosphorus Compounds
  • Prostate (enzymology)
  • Prostatic Neoplasms (diagnosis, enzymology)
  • Radioimmunoassay

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