Early-onset preeclampsia, triploidy and fetal hydrops.

Abstract

Early-onset preeclampsia (16-24 weeks) is frequently associated with fetal and placental anomalies. Hydatidiform mole, fetoplacental triploidy with partial molar changes and idiopathic hydrops fetalis are commonly associated ones. Two patients had severe, early-onset preeclampsia and ultrasonically documented fetal anomalies, one fetal triploidy, the other idiopathic hydrops with normal karyotype. The management of early-onset preeclampsia benefits from ultrasonography, and an aggressive search for fetal anomalies is recommended. Seventy-two percent of cases of early-onset preeclampsia in our institution were associated with significant fetal and placental malformations. An immunologic basis of the preeclampsia in these cases seems likely but remains unproven.

• Authors: F F Broekhuizen, R Elejalde, P R Hamilton
• Journal: The Journal of reproductive medicine (J Reprod Med) Vol. 28 Issue 3 Pg. 223-6 (Mar 1983) ISSN: 0024-7758 [Print] United States
• PMID: 6854556 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Aneuploidy
• Edema (complications, diagnosis)
• Female
• Fetal Diseases (complications, diagnosis)
• Humans
• Pre-Eclampsia (complications, diagnosis)
• Pregnancy