Studies on high density lipoproteins in fish eye disease.

Abstract

Serum high density lipoproteins (HDL) were isolated by preparative ultracentrifugation from two patients with fish eye disease (FED). Compared to HDL from control subjects the HDL particles of FED were characterized by their abnormally small size and a relative enrichment with polar lipids. No qualitative abnormalities of the HDL apolipoproteins were revealed upon polyacrylamide disc gel electrophoresis or isoelectric focusing. The plasma pool of apolipoprotein A was reduced by 90%.

• Authors: L A Carlson, L Holmquist
• Journal: Acta medica Scandinavica (Acta Med Scand) Vol. 213 Issue 3 Pg. 177-82 ( 1983) ISSN: 0001-6101 [Print] Sweden
• PMID: 6846063 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Apolipoproteins
• Cholesterol Esters
• Lipoproteins, HDL
• Phospholipids
• Triglycerides
• Cholesterol

Topics

• Adult
• Apolipoproteins (genetics)
• Cholesterol (analysis)
• Cholesterol Esters (analysis)
• Corneal Opacity (blood)
• Female
• Humans
• Lipoproteins, HDL (analysis)
• Male
• Middle Aged
• Phospholipids (analysis)
• Triglycerides (analysis)