Abstract |
A total of 80 subjects with benign and malignant breast disease and healthy controls were studied for reactivity to T-antigen, MN- antigens and phytohemagglutinin (PHA) using the lymphocyte blastogenesis assay. No differences were detected between controls and patients with benign or malignant breast disease in reactivity to T- and MN- antigens. Moreover, there was no differential response to T- and MN- antigens among patients with breast cancer. PHA reactivity, although similar between groups as a whole, was diminished in patients with advanced carcinoma. These findings indicate that T-antigen fails to induce cell mediated immunity in patients with breast cancer.
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Authors | D R Howard |
Journal | Cancer
(Cancer)
Vol. 51
Issue 11
Pg. 2053-6
(Jun 01 1983)
ISSN: 0008-543X [Print] United States |
PMID | 6839295
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)
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Chemical References |
- Antigens, Neoplasm
- MNSs Blood-Group System
- Phytohemagglutinins
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Topics |
- Adult
- Antigens, Neoplasm
(immunology)
- Breast Neoplasms
(immunology)
- Female
- Humans
- Immunity, Cellular
- Lymphocyte Activation
- MNSs Blood-Group System
(immunology)
- Middle Aged
- Phytohemagglutinins
(pharmacology)
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