Tularemia complicated by acute renal failure.

Abstract

Acute renal failure has been a rare, uniformly fatal complication of infection with Francisella tularensis. The literature suggests that either acute tubular necrosis, interstitial nephritis, or glomerulonephritis may be responsible for this syndrome. We have described a patient with tularemia who had nonoliguric acute renal failure probably due to interstitial nephritis and who recovered slowly but spontaneously during antimicrobial therapy with doxycycline.

• Authors: W S Tilley, R W Garman, W J Stone
• Journal: Southern medical journal (South Med J) Vol. 76 Issue 2 Pg. 273-4 (Feb 1983) ISSN: 0038-4348 [Print] United States
• PMID: 6823614 (Publication Type: Case Reports, Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

Chemical References

• Doxycycline

Topics

• Acute Kidney Injury (drug therapy, etiology)
• Aged
• Cerebrospinal Fluid (analysis)
• Doxycycline (therapeutic use)
• Humans
• Male
• Nephritis (drug therapy, etiology)
• Tularemia (complications, diagnosis, immunology)