Exercise-induced asthma diagnosis and prevention with a metered dose aerosol formulation of sodium cromoglycate.

Abstract	The protective effect of sodium cromoglycate against the bronchospasm induced by exercise in 10 asthmatic subjects was compared with that of placebo in a single-blind study. The drug, which was administered by means of a metered dose aerosol, at a lower dose than is currently used in the therapy of asthma, was shown to be significantly more effective than placebo in preventing postexercise changes in all the respiratory function parameters measured (VC, FEV1, PEFR, MEFR50, TGV and SGaw).
Authors	C M Sanguinetti, S Gasparini, F Bonifazi, L S Vennarucci
Journal	Respiration; international review of thoracic diseases (Respiration) Vol. 43 Issue 2 Pg. 132-41 ( 1982) ISSN: 0025-7931 [Print] Switzerland
PMID	6808622 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)
Chemical References	Cromolyn Sodium
Topics	Adolescent Adult Asthma (drug therapy) Asthma, Exercise-Induced (drug therapy) Child Cromolyn Sodium (administration & dosage, pharmacology, therapeutic use) Female Humans Lung (drug effects, physiopathology) Male Middle Aged Respiratory Function Tests

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