Contact allergic reactions to diphenylthiourea and phenylisothiocyanate in PVC adhesive tape.

Abstract

28 patients reacting to a PVC adhesive tape used in routine patch testing gave positive reactions to diphenylthiourea (DPTU) and to phenylisothiocyanate (PITC) in low concentrations. DPTU is a heat stabilizer in the PVC and is partly decomposed to PITC. The two substances were found in another type of PVC. Thioureas giving isothiocyanates are also used in certain types of rubber. Isothiocyanates are present in plants, mainly of the Cruciferae family, and are also formed from thiuram sulfides and thiocarbamates. The connection between isothiocyanates derived from different sources should be investigated.

• Authors: S Fregert, L Trulson, E Zimerson
• Journal: Contact dermatitis (Contact Dermatitis) Vol. 8 Issue 1 Pg. 38-42 (Jan 1982) ISSN: 0105-1873 [Print] England
• PMID: 6802568 (Publication Type: Journal Article)

Chemical References

• Adhesives
• Isothiocyanates
• Thiocyanates
• phenylisothiocyanate
• Polyvinyl Chloride
• diphenylthiourea
• Thiourea

Topics

• Adhesives (adverse effects)
• Dermatitis, Contact (etiology)
• Female
• Humans
• Isothiocyanates
• Male
• Patch Tests
• Polyvinyl Chloride
• Thiocyanates (adverse effects)
• Thiourea (adverse effects, analogs & derivatives)