Chemotherapy of Sarcosporidiosis and theileriosis in domestic animals.

Abstract

In goats infected with Sarcocystis capracanis and sheep infected with S. Ovicanis prophylactical application of halofuginone prevented clinical symptoms but also prevented the development of immunity to homologous challenge. Halofuginone was most effective in the treatment of acute sarcosporidiosis at a dose of 0.67 mg/kg b. w. on two successive days in both goats and sheep. In acute bovine theileriosis (Theileria parva and T. annulata) halofuginone was effective at a single dose about of 1.2 to 2 mg/kg b.w. Cattle recovered from theileriosis through treatment were immune to homologous challenge.

• Authors: W P Voigt, A O Heydorn
• Journal: Zentralblatt fur Bakteriologie, Mikrobiologie und Hygiene. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie = International journal of microbiology and hygiene. A, Medical microbiology, infectious... (Zentralbl Bakteriol Mikrobiol Hyg A Med Mikrobiol Infekt Parasitol) Vol. 250 Issue 1-2 Pg. 256-9 ( 1981) ISSN: 0174-3031 [Print] Germany
• PMID: 6797156 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Coccidiostats
• Drug Combinations
• Piperidines
• Quinazolines
• Quinazolinones
• Sulfadoxine
• Trimethoprim
• halofuginone
• Oxytetracycline

Topics

• Animals
• Cattle
• Coccidiostats (therapeutic use)
• Drug Combinations
• Goats
• Oxytetracycline (therapeutic use)
• Piperidines (therapeutic use)
• Quinazolines (therapeutic use)
• Quinazolinones
• Sarcocystosis (veterinary)
• Sheep
• Sheep Diseases (drug therapy)
• Sulfadoxine (therapeutic use)
• Theileriasis (drug therapy)
• Trimethoprim (therapeutic use)