Inhibition of DMBA carcinogenesis of hamster buccal pouch by phenanthrene and dimethylnaphthalene.

Abstract

Phenanthrene (Phe) and to a lesser degree 1,4-dimethylnaphthalene (DMeN) were each found to retard the development of epidermoid carcinomas in hamster buccal pouch induced by the thrice weekly application of a 0.5 per cent solution of 7,12-dimethylbenz[a]anthracene (DMBA) in heavy mineral oil.

• Authors: D S Malament, G Shklar
• Journal: Carcinogenesis (Carcinogenesis) Vol. 2 Issue 8 Pg. 723-9 ( 1981) ISSN: 0143-3334 [Print] England
• PMID: 6793258 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Benz(a)Anthracenes
• Naphthalenes
• Phenanthrenes
• phenanthrene
• 9,10-Dimethyl-1,2-benzanthracene
• 1,4-dimethylnaphthalene

Topics

• 9,10-Dimethyl-1,2-benzanthracene (antagonists & inhibitors)
• Animals
• Benz(a)Anthracenes (antagonists & inhibitors)
• Cheek
• Cricetinae
• Female
• Male
• Mesocricetus
• Mouth Neoplasms (chemically induced, pathology, prevention & control)
• Naphthalenes (pharmacology)
• Neoplasms, Experimental (chemically induced, pathology, prevention & control)
• Phenanthrenes (pharmacology)
• Time Factors