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Bone changes in end-stage oxalosis.

Abstract
Primary hyperoxaluria is a rare metabolic disease characterized by exaggerated production of oxalic acid. Clinically the disease is characterized by recurrent calcium nephrolithiasis, progressive renal failure, and early death in uremia. As the regular dialysis treatment may prolong survival, a new syndrome may develop. This is due to intense and continuous deposition of calcium oxalate crystals in soft and bone tissues. The radiologic aspects of oxalate deposition in four adult patients on chronic renal dialysis with histologic and clinical evidence of massive bone oxalosis are reported.
AuthorsD Brancaccio, A Poggi, C Ciccarelli, F Bellini, C Galmozzi, I Poletti, Q Maggiore
JournalAJR. American journal of roentgenology (AJR Am J Roentgenol) Vol. 136 Issue 5 Pg. 935-9 (May 1981) ISSN: 0361-803X [Print] United States
PMID6784531 (Publication Type: Case Reports, Comparative Study, Journal Article)
Chemical References
  • Parathyroid Hormone
  • Calcium Oxalate
Topics
  • Adolescent
  • Adult
  • Bone Diseases, Metabolic (diagnostic imaging, metabolism, pathology)
  • Bone Resorption
  • Bone and Bones (diagnostic imaging, pathology)
  • Calcium Oxalate (metabolism, urine)
  • Female
  • Humans
  • Hyperparathyroidism (metabolism)
  • Kidney Calculi (metabolism)
  • Kidney Failure, Chronic (metabolism)
  • Male
  • Parathyroid Hormone (blood)
  • Radiography
  • Time Factors
  • Uremia (metabolism)

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