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Antitumor activities and estrogen receptor interactions of the metabolites of the antiestrogens C1628 and U23,469 in the 7,12-dimethylbenz(a)anthracene-induced rat mammary tumor system.

AuthorsE A Rorke, B S Katzenellenbogen
JournalCancer research (Cancer Res) Vol. 41 Issue 4 Pg. 1257-62 (Apr 1981) ISSN: 0008-5472 [Print] United States
PMID6783294 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • Estrogen Antagonists
  • Naphthalenes
  • Propylene Glycols
  • Pyrrolidines
  • Receptors, Estrogen
  • Tetrahydronaphthalenes
  • U 23469
  • Estradiol
  • 9,10-Dimethyl-1,2-benzanthracene
  • Nitromifene
  • Peroxidases
Topics
  • 9,10-Dimethyl-1,2-benzanthracene
  • Animals
  • Binding, Competitive
  • Cytosol (metabolism)
  • Estradiol (metabolism)
  • Estrogen Antagonists (metabolism, therapeutic use)
  • Female
  • Mammary Neoplasms, Experimental (chemically induced, drug therapy, metabolism)
  • Naphthalenes (therapeutic use)
  • Nitromifene (pharmacology)
  • Organ Size (drug effects)
  • Peroxidases
  • Propylene Glycols (metabolism, therapeutic use)
  • Pyrrolidines (pharmacology)
  • Rats
  • Receptors, Estrogen (metabolism)
  • Tetrahydronaphthalenes (metabolism, therapeutic use)
  • Uterus (drug effects, metabolism)

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