[Activation of carboxylation as a factor in correcting the metabolic disorder in diabetes mellitus].

Abstract

The paper deals with studies of the effect of the 10-day complex therapy with carbostimulin application on the content of the tricarboxylic cycle and glycolysis metabolites, total lipids, cholesterol, triglycerides in blood and potassium and sodium in blood serum of patients with diabetes mellitus. It is established that under the effect of carbostimulin the content of oxaloacetate, lactate and alpha-glycerophosphate becomes normal, the lactate/pyruvate ratio elevated in diabetes decreases, which evidences for intensification of reduction processes in the cytoplasm.

• Authors: A V Shcherbak, N D Dzvonkevich, M F Gulyĭ
• Journal: Ukrainskii biokhimicheskii zhurnal (1978) (Ukr Biokhim Zh (1978)) 1981 Jan-Feb Vol. 53 Issue 1 Pg. 50-3 ISSN: 0201-8470 [Print] Ukraine
• Vernacular Title: Aktivatsiia karboksilirovaniia kak faktor korrektsii narushennogo obmena veshchestv pri sakharnom diabete.
• PMID: 6782726 (Publication Type: English Abstract, Journal Article)

Chemical References

• Lipids
• Triglycerides
• Carbon Dioxide
• Cholesterol
• Sodium
• Potassium

Topics

• Carbon Dioxide (metabolism)
• Cholesterol (blood)
• Citric Acid Cycle
• Diabetes Mellitus (blood, drug therapy, metabolism)
• Glycolysis
• Humans
• Lipids (blood)
• Potassium (blood)
• Sodium (blood)
• Triglycerides (blood)