The early enzymatic debridement and grafting of deep dermal burns to the hand.

Abstract

Thirty-four hands in 24 patients with clinically diagnosed, deep second-degree burns have been treated for 24 hours, immediately after the burn with Sutilains bacterial enzymatic ointment. The ages of the patients range from 16 months to 65 years. Follow-up was from 3 to 12 months. After 24 hours' treatment with the enzyme, the patient is taken to the operating room, where the soft eschar is scraped from the wound and thin split-thickness grafts are applied. Ninety-one percent had full take of the grafts and were able to move their hands actively and passively through a full range of movement within 1 week after the burn. The long-term aesthetic and functional results were excellent.

• Authors: T D Gant
• Journal: Plastic and reconstructive surgery (Plast Reconstr Surg) Vol. 66 Issue 2 Pg. 185-90 (Aug 1980) ISSN: 0032-1052 [Print] United States
• PMID: 6773085 (Publication Type: Journal Article)

Chemical References

• Fibrinolytic Agents
• Ointments
• Peptide Hydrolases

Topics

• Adolescent
• Adult
• Aged
• Bacillus subtilis (enzymology)
• Bandages
• Burns (surgery)
• Child
• Child, Preschool
• Debridement (methods)
• Evaluation Studies as Topic
• Fibrinolytic Agents
• Hand Injuries (surgery)
• Humans
• Infant
• Middle Aged
• Ointments
• Peptide Hydrolases (administration & dosage)
• Preoperative Care (methods)
• Skin Transplantation
• Time Factors
• Transplantation, Autologous