[Value of Noxyflex for peritoneal toilet in acute generalized peritonitis. A controlled study of 48 cases (author's transl)].

Abstract

The efficacy of Noxythiolin in solution for peritoneal toilet during operation on 48 patients with acute generalized peritonitis was evaluated. The trial was prospective, with random selection of patients who were divided into two groups with identical backgrounds, initial affections, and therapies applied. No significant differences were noted in prognosis, bacteriological findings or subsequent course in the survivors in the two groups. The only favorable effect noted in the group treated with Noxythiolin was the frequency with which further operations had to be performed, but the difference was nos significant. Though the use of peritoneal antiseptics isjustified when positive bacteriological test are reported, the determining element in peritoneal toilet appears to be the volume of liquid employed, independently of its composition.

• Authors: G Champault, P Frileux, F Michot, F Psalmon, M Hornstein, J C Patel
• Journal: Journal de chirurgie (J Chir (Paris)) Vol. 117 Issue 2 Pg. 81-6 (Feb 1980) ISSN: 0021-7697 [Print] France
• Vernacular Title: La toilette péritonéale dans les péritonites aiguës généralisées. Influence du Noxyflex. Essai contrôlé de 48 cas.
• PMID: 6769930 (Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, English Abstract, Journal Article)

Chemical References

• Solutions
• Noxythiolin
• Thiourea

Topics

• Acute Disease
• Aged
• Clinical Trials as Topic
• Female
• Humans
• Intraoperative Care
• Male
• Middle Aged
• Noxythiolin (therapeutic use)
• Peritoneum (microbiology)
• Peritonitis (complications, microbiology, therapy)
• Postoperative Period
• Prognosis
• Recurrence
• Solutions
• Therapeutic Irrigation (methods)
• Thiourea (analogs & derivatives)