Abstract |
17 thin grafts of corpse skin containing neavi, were grafted onto the back of athymic mice. All the grafts took. The naevi were than deeply incised on 3 occasions. No evidence of abnormal healing, of pigment release, or of malignant transformation, appeared. 10 epidermal grafts of superficial malignant melanoma, taken from 4 different patients, took successfully. In 7 of these, superficial ulcerations appeared but were definitively re-epithelialised from the adjacent Mouse skin. 5 and 7 months later, the melanoma are stable, without local extensions, infiltration or apparent metastase. Despite the absence of an inflammatory reaction, these melanoma are paradoxically quiescent in nude Mice.
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Authors | A Duprez |
Journal | Comptes rendus des seances de l'Academie des sciences. Serie D, Sciences naturelles
(C R Seances Acad Sci D)
Vol. 290
Issue 6
Pg. 461-4
(Feb 11 1980)
ISSN: 0567-655X [Print] France |
Vernacular Title | Greffes chez la Souis athymique nu/nu de peaux humaines porteuses de naevi ou de naevocarcinomes superficiels : étude macroscopique et microscopique. |
PMID | 6767555
(Publication Type: English Abstract, Journal Article)
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Topics |
- Animals
- Cell Transformation, Neoplastic
(pathology)
- Graft Survival
- Humans
- Male
- Melanoma
(pathology)
- Mice
- Mice, Nude
- Neoplasm Metastasis
- Neoplasm Transplantation
- Nevus
(pathology)
- Skin
(pathology)
- Skin Neoplasms
(pathology)
- Skin Pigmentation
- Skin Transplantation
- Transplantation, Heterologous
(methods)
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