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Acyclovir in the treatment of herpetic keratitis.

Abstract
Fourty-three eyes with active dendritic keratitis, nearly one third of which had failed to respond to other antiviral agents, were treated with acyclovir with or without preceding debridement. The patients were randomly selected. No statistical difference could be demonstrated between the 2 groups in terms of rate of healing or in efficacy of cure. Acyclovir also seemed to be effective in stromal corneal lesions. There were only minor side effects.
AuthorsK B Jensen, S H Nissen, F Jessen
JournalActa ophthalmologica (Acta Ophthalmol (Copenh)) Vol. 60 Issue 4 Pg. 557-63 (Aug 1982) ISSN: 0001-639X [Print] Denmark
PMID6760657 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
Chemical References
  • Antiviral Agents
  • Ophthalmic Solutions
  • acyclovir triphosphate
  • Chloramphenicol
  • Acyclovir
Topics
  • Acyclovir (analogs & derivatives, therapeutic use)
  • Antiviral Agents (therapeutic use)
  • Chloramphenicol (therapeutic use)
  • Clinical Trials as Topic
  • Drug Therapy, Combination
  • Humans
  • Keratitis, Dendritic (drug therapy)
  • Ophthalmic Solutions

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