Abstract |
The in-vitro bactericidal effect of serum for Klebsiella rhinoscleromatis was tested. Experiments with C2-deficient and hypogammaglobulinaemic human sera suggested that killing depended on activation of the classical complement pathway, although the alternative pathway probably amplified the effect. Serum from a patient with active rhinoscleroma, and another cured of the disease, showed normal killing.
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Authors | M E North, C A Newton, D J Wright, A D Webster |
Journal | Journal of medical microbiology
(J Med Microbiol)
Vol. 15
Issue 2
Pg. 267-72
(May 1982)
ISSN: 0022-2615 [Print] England |
PMID | 6754946
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Agammaglobulinemia
(immunology)
- Blood Bactericidal Activity
- Complement C2
(deficiency)
- Granuloma
(immunology)
- Humans
- Klebsiella Infections
(immunology)
- Klebsiella pneumoniae
(immunology, metabolism)
- Nasopharyngeal Diseases
(immunology)
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