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Treatment of perennial allergic rhinitis by local hyperthermia.

Abstract
Ninety-five patients with documented perennial allergic rhinitis have been treated with local hyperthermia of the nasal passages in a randomized double-blind trial. The treatment consisted of one series of three 30-min insufflations of humidified air at 43 degrees C at a 2-hr interval. In the active treatment group, 75% (P less than 0.00003) and 68% (P less than 0.00001) of the patients were free of symptoms 1 week and 1 month, respectively, after treatment, compared with a 28% and 17% response in the placebo group. We conclude that local hyperthermia is effective in the treatment of perennial allergic rhinitis.
AuthorsA Yerushalmi, S Karman, A Lwoff
JournalProceedings of the National Academy of Sciences of the United States of America (Proc Natl Acad Sci U S A) Vol. 79 Issue 15 Pg. 4766-9 (Aug 1982) ISSN: 0027-8424 [Print] United States
PMID6750609 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
Topics
  • Adolescent
  • Adult
  • Aged
  • Child
  • Child, Preschool
  • Clinical Trials as Topic
  • Double-Blind Method
  • Female
  • Follow-Up Studies
  • Hot Temperature
  • Humans
  • Male
  • Middle Aged
  • Rhinitis, Allergic, Perennial (therapy)

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