Tumor detection with some 99mTc-labeled S-containing amino acids.

Abstract

99mTc-labeled L-cysteine, DL-homocysteine, and S-carbamyl-L-cysteine were prepared and tested for effectiveness in gamma camera imaging and for bioradiodistribution in mice bearing Ehrlich solid tumors. Among these labeled compounds, 99mTc-DL-homocysteine seems most promising for the nuclear medical imaging of tumors.

• Authors: O Tamemasa, A Takeda, R Goto
• Journal: Gan (Gan) Vol. 75 Issue 5 Pg. 395-402 (May 1984) ISSN: 0016-450X [Print] Japan
• PMID: 6745561 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Homocysteine
• S-carbamylcysteine
• Technetium
• Cysteine

Topics

• Animals
• Carcinoma, Ehrlich Tumor (diagnostic imaging)
• Cysteine (analogs & derivatives, metabolism)
• Homocysteine (metabolism)
• Male
• Mice
• Mice, Inbred Strains
• Neoplasms, Experimental (diagnostic imaging)
• Radionuclide Imaging
• Technetium
• Tissue Distribution