Abstract |
Giemsa-banded chromosomal analysis of two unilateral retinoblastoma tumors from unrelated patients with normal constitutional chromosomes revealed near-diploid karyotypes with multiple structural rearrangements. The two tumors shared aberrations of trisomy 1q, monosomy 16 and 17, and 21p+. Other aberrations were unique to each tumor. One tumor expressed a del(13) and trisomy 6p.
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Authors | M L Workman, S W Soukup |
Journal | Cancer genetics and cytogenetics
(Cancer Genet Cytogenet)
Vol. 12
Issue 4
Pg. 365-70
(Aug 1984)
ISSN: 0165-4608 [Print] United States |
PMID | 6744228
(Publication Type: Journal Article)
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Topics |
- Adult
- Chromosome Aberrations
- Chromosome Banding
- Chromosomes, Human, 1-3
- Chromosomes, Human, 16-18
- Chromosomes, Human, 21-22 and Y
- Eye Neoplasms
(genetics)
- Humans
- Karyotyping
- Male
- Retinoblastoma
(genetics)
- Trisomy
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