Influence of ethoxyquin on the utilization of selenium by the chick.

Abstract

Experiments showed that commonly used concentrations of dietary ethoxyquin (6-ethoxy-2,2,4-trimethyl-1,2-dihydroxyquinoline) spare the selenium requirement of the vitamin E-deficient chick according to the following function: log Y = -0.0011X - 0.7741, where Y = Se requirement (ppm) and X = dietary ethoxyquin (ppm). The basis of the sparing effect appeared to be metabolic; (a) ethoxyquin was effective in alleviating exudative diathesis when fed (physiologically and chronologically) separately from selenium, and (b) ethoxyquin was effective in promoting increases in the plasma of the selenium-containing enzyme, glutathione peroxidase.

• Authors: G F Combs Jr
• Journal: Poultry science (Poult Sci) Vol. 57 Issue 1 Pg. 210-22 (Jan 1978) ISSN: 0032-5791 [Print] England
• PMID: 674008 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Quinolines
• Vitamin E
• Ethoxyquin
• Glutathione Peroxidase
• Selenium

Topics

• Animals
• Chickens (metabolism)
• Ethoxyquin (administration & dosage, pharmacology)
• Glutathione Peroxidase (blood)
• Poultry Diseases (metabolism, prevention & control)
• Quinolines (pharmacology)
• Selenium (administration & dosage, deficiency, metabolism)
• Vitamin E (administration & dosage, blood)
• Vitamin E Deficiency (metabolism, prevention & control, veterinary)