A case of
meningioma that developed 37 years after irradiation
therapy for vascular
nevus of the scalp over the right frontoparietal region was reported. A 49-year-old male was admitted to the hospital of Gifu University on October 26, 1979, because of a
generalized seizure. He had been born with a vascular
nevus affecting the right frontoparietal scalp, for which he began receiving local irradiation at the age of 12. The total dose was not known because the only source of information regarding this treatment was the patient's memory. From the age of 17, the suffered from occasional attacks of
dysesthesia in the left side of his body without
consciousness disorder. He otherwise remained well for the intervening 37 years. Upon admission, he had a vascular
nevus remaining with post irradiation skin changes over the right frontoparietal region. General and neurological examination were not remarkable. Right carotid angiogram and CT scan disclosed the presence of a right frontal
tumor. A right frontotemporal
craniotomy was performed on December 4, 1979 and a hard
tumor was found firmly attached to the dura and bone at the right site. All visible
tumor and involved bone were completely removed without difficulty. Histological examination of the surgical specimen showed the characteristic features of a
transitional meningioma. There was no evidence of
malignancy in the sections examined. Since Mann et al reported a malignant
meningioma following irradiation
therapy for
optic nerve glioma, there have been many reports, over seventy cases of so-called
radiation-induced meningioma. However, a
meningioma following irradiation
therapy for vascular
nevus of scalp or face is exceedingly rare.(ABSTRACT TRUNCATED AT 250 WORDS)