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A soluble beta-1,3-D-glucan derivative potentiates the cytostatic and cytolytic capacity of mouse peritoneal macrophages in vitro.

Abstract
An aminated beta-1,3-D-glucan derivative of curdlan is reported to render macrophages cytostatic to L-929 cells and to potentiate macrophage cytotoxicity to the tumor cells in vitro.
AuthorsR Seljelid, J Bøgwald, J Hoffman, O Larm
JournalImmunopharmacology (Immunopharmacology) Vol. 7 Issue 1 Pg. 69-73 (Feb 1984) ISSN: 0162-3109 [Print] Netherlands
PMID6715145 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Glucans
  • beta-Glucans
  • beta-1,3-glucan
Topics
  • Animals
  • Ascitic Fluid
  • Cell Line
  • Cell Transformation, Neoplastic
  • Cells, Cultured
  • Cytotoxicity, Immunologic (drug effects)
  • Dose-Response Relationship, Drug
  • Fibroblasts
  • Glucans (pharmacology)
  • Macrophages (drug effects, immunology)
  • Mice
  • Mice, Inbred C3H
  • Mice, Inbred DBA
  • beta-Glucans

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