[Acute voluntary carpipramine poisoning with ventricular tachycardia].

Abstract

A case of carpipramine overdose is reported. The patient was admitted with ventricular tachycardia 4 h after taking 2.40 g of the drug. This disappeared at the sixth hour. In overdoses with other tricyclics, ventricular tachycardia was successfully treated within 30 min of starting a sodium lactate perfusion. In the case presented, reversal of the ventricular tachycardia coincided with the half-life of the drug; the effects of perfusing 1000 ml sodium lactate over 2 h seemed doubtful. This sodium resistance may be related to a relative hypokalemia (3.4 mmol X 1(-1) ). The use of sodium lactate for the treatment of overdoses with drugs with short-half lives appeared questionable.

• Authors: J P Racle, G Maman, C Beligon, D Curabet
• Journal: Annales francaises d'anesthesie et de reanimation (Ann Fr Anesth Reanim) Vol. 3 Issue 1 Pg. 52-3 ( 1984) ISSN: 0750-7658 [Print] France
• Vernacular Title: Intoxication volontaire aiguë par la carpipramine avec tachycardie ventriculaire.
• PMID: 6703422 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Anti-Anxiety Agents
• Dibenzazepines
• Benzodiazepines
• carpipramine

Topics

• Acute Disease
• Adult
• Anti-Anxiety Agents
• Benzodiazepines
• Dibenzazepines (poisoning)
• Electrocardiography
• Female
• Heart Ventricles
• Humans
• Tachycardia (chemically induced)