HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Heart failure associated with high plasma 10-hydroxynortriptyline levels.

Abstract
The authors describe a patient who developed congestive heart failure and had a high plasma concentration of 10-hydroxynortriptyline. They discuss the need for further research to define the contribution of antidepressants' active metabolites to toxic and therapeutic effects.
AuthorsR C Young, G S Alexopoulos, C A Shamoian, A K Dhar, H Kutt
JournalThe American journal of psychiatry (Am J Psychiatry) Vol. 141 Issue 3 Pg. 432-3 (Mar 1984) ISSN: 0002-953X [Print] United States
PMID6703113 (Publication Type: Case Reports, Journal Article)
Chemical References
  • 10-hydroxynortriptyline
  • Nortriptyline
Topics
  • Aged
  • Depressive Disorder (blood, drug therapy)
  • Heart Failure (blood, chemically induced, metabolism)
  • Humans
  • Hydroxylation
  • Male
  • Nortriptyline (adverse effects, analogs & derivatives, blood, metabolism, therapeutic use)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: