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Glycohemoglobin as a screening test for gestational diabetes.

Abstract
This study evaluated the feasibility of utilizing hemoglobin A1c as a screening test for gestational diabetes. We compared this test in 82 women in the third trimester of pregnancy to a glucose tolerance test in which a glucose load of 100 gm was used. At its best index of correlation, hemoglobin A1c at 7% is concordant with the glucose tolerance test in 69% of the cases, false positive in 41%, and false negative in 26%. Though the two procedures correlate very well, the high incidence of false negative and positive for hemoglobin A1c make this test inadequate as a screening procedure for gestational diabetes.
AuthorsR Artal, G M Mosley, F J Dorey
JournalAmerican journal of obstetrics and gynecology (Am J Obstet Gynecol) Vol. 148 Issue 4 Pg. 412-4 (Feb 15 1984) ISSN: 0002-9378 [Print] UNITED STATES
PMID6695998 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Hemoglobin A, Glycosylated
Topics
  • Diabetes Mellitus (diagnosis)
  • Female
  • Glucose Tolerance Test
  • Hemoglobin A, Glycosylated (analysis)
  • Humans
  • Pregnancy
  • Pregnancy in Diabetics
  • Prospective Studies

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