Glycohemoglobin as a screening test for gestational diabetes.

This study evaluated the feasibility of utilizing hemoglobin A1c as a screening test for gestational diabetes. We compared this test in 82 women in the third trimester of pregnancy to a glucose tolerance test in which a glucose load of 100 gm was used. At its best index of correlation, hemoglobin A1c at 7% is concordant with the glucose tolerance test in 69% of the cases, false positive in 41%, and false negative in 26%. Though the two procedures correlate very well, the high incidence of false negative and positive for hemoglobin A1c make this test inadequate as a screening procedure for gestational diabetes.
AuthorsR Artal, G M Mosley, F J Dorey
JournalAmerican journal of obstetrics and gynecology (Am J Obstet Gynecol) Vol. 148 Issue 4 Pg. 412-4 (Feb 15 1984) ISSN: 0002-9378 [Print] UNITED STATES
PMID6695998 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Hemoglobin A, Glycosylated
  • Diabetes Mellitus (diagnosis)
  • Female
  • Glucose Tolerance Test
  • Hemoglobin A, Glycosylated (analysis)
  • Humans
  • Pregnancy
  • Pregnancy in Diabetics
  • Prospective Studies

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!

Choose Username:
Verify Password: