[Antisilicotic properties of polyethylene-piperazine N-oxide--a new polymeric compound].

Abstract

A high antisilicotic activity of a new polymeric compound--polyethylene-piperazine N-oxide (molecular mass 5000--8000, degree of exidation--80 per cent), synthetized on the basis of aliphatic amine, was shown as against polyvinylpyridine-N-oxide in experiments conducted on albino rats with silicosis.

• Authors: L M Kupina, A S Ivanova, V I Fedorova, A V Nekrasov, N G Puchkova, P K Tarasenko
• Journal: Farmakologiia i toksikologiia (Farmakol Toksikol) 1978 Jun-Aug Vol. 41 Issue 4 Pg. 433-8 ISSN: 0014-8318 [Print] Russia (Federation)
• Vernacular Title: O protivosilikoticheskikh svoistvakh novogo polimernogo soedineniia N-okisi polietilenpiperazina.
• PMID: 668868 (Publication Type: English Abstract, Journal Article)

Chemical References

• Piperazines
• Polyethylenes
• Polyvinylpyridine N-Oxide

Topics

• Animals
• Lung (pathology)
• Piperazines (therapeutic use)
• Polyethylenes (therapeutic use)
• Polyvinylpyridine N-Oxide (therapeutic use)
• Rats
• Silicosis (drug therapy, pathology)